Laminin Rabbit anti-Human, Rat, Polyclonal, Invitrogen™

Description

This antibody labels basement membrane laminin proteins surrounding normal vessels, glands, muscles, nerves, fat and decidual cells separating these from abutting connective tissues.

Extracellular matrix (ECM) surrounds and separates most tissue compartments, determines tissue architecture and dynamically interacts with its surrounding cells. The basement membrane is a part of the ECM and is composed of collagens, proteoglycans, elastin and several glycoproteins of which laminin is the most abundant. Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains Dystroglycan is a major laminin receptor in muscle and epithelia, and nidogen is a high-affinity laminin-binding protein important for basement-membrane assembly.