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CD28 Mouse anti-Human, PE, Clone: L293, BD

Product Code. 15866128
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100 Tests
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15866128 100 Tests Each
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Product Code. 15866128 Supplier BD Biosciences Supplier No. 348047

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Description

Mouse Monoclonal Antibody

The CD28 antibody, clone L293, is derived from hybridization of Sp2/0-Ag14 mouse myeloma cells with spleen cells from BALB/c mice immunized with the HPB-ALL T-cell line.

The CD28 antigen, a disulfide-linked homodimeric glycoprotein, Mr 44 kilodaltons (kd), is a cell-adhesion molecule (CAM) and functions as the ligand for CD80 (B7-1) and CD86 (B7-2) antigens, which are present on activated B lymphocytes, monocytes, and dendritic cells. Interaction of the CD28 antigen with CD80 or CD86 antigens, or both, co-stimulates CD2 and CD3 antigen/T-cell antigen receptor (TCR)–dependent T-cell–mediated proliferation and cytotoxicity.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD28
Applications Flow Cytometry
Classification Monoclonal
Clone L293
Concentration 25μg/mL
Conjugate PE
Formulation Phosphate buffered saline with gelatin and 0.1% sodium azide.
Host Species Mouse
Quantity 100 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Isotype IgG1 κ
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For Research Use Only.

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