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CD16/CD32 Rat anti-Mouse, Clone: 93, eBioscience™

Rat Monoclonal Antibody

Marke:  Affymetrix eBioscience 14-0161-82

Weitere Details : Gewicht : 0.01000kg

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Artikelnummer. 15236827

  • 86.75 € / 100 Mikrogramm


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Beschreibung

Beschreibung

CD16 is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by natural killer (NK) cells, and some T cells and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC (antibody dependent cell mediated cytotoxicity) by NK cells. IN comparison, CD32 is a 40 kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII), and mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets. Further, CD32 is involved in the phagocytosis of immune complexes, the regulation of antibody production by B-cells, and variations of the CD32 gene may increase vulnerability to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms of CD32 have been found.
Spezifikation

Spezifikation

CD16/CD32
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P08101
FCGR3, FCGR3A, FCGR3B, CD16A, CD16B, Fc gamma Receptor III, Fc gamma Receptor 3, RP11-5K23.1, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, FCGR2, CD32, Fc gamma Receptor II, CD32 receptor 2, Fc gamma Receptor 2, FCGR2A, FCGR2B, FCGR2C, Low affinity immunoglobulin gamma Fc region receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, FCG2, Low affinity immunoglobulin gamma Fc region receptor II-c, Fc-gamma RII-c, Fc-gamma-RIIc, FcRII-c, FGFR2B
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry, Functional Assay, Neutralization
93
Unconjugated
Fcgr2b
Liquid
Fcgr2b
IgG2a, lambda
100 μg
4° C
Primary
14130
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