missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Analysis Products
  4. Cell Based Assays
  5. Apoptosis Reagents and Kits
  6. STEMCELL Technologies Annexin V, APC

STEMCELL Technologies Annexin V, APC

Product Code. 17107561
Encompass_Preferred
Click to view available options
Quantity:
100 Tests
25 Tests
Unit Size:
100 tests
25 tests
This item is not returnable. View return policy

Product Code. 17107561

Brand: STEMCELL Technologies 1000328

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

A cellular protein for detection of apoptotic cells, PE-conjugated

  • Annexin V is a member of the annexin family of proteins that bind to membrane phospholipids in the presence of calcium
  • This dye has high affinity for phosphatidylserine (PS) that is present in the inner leaflet of the plasma membrane
  • During early-stage cell apoptosis, PS is translocated from the inner to the outer leaflet of the plasma membrane, exposing it to the external environment
  • Annexin V, a characteristic marker for early cell apoptosis, detects the translocation of PS to the external environment
  • Annexin V is used along with viability dyes such as 7-AAD (Catalog #75001) or Propidium Iodide (Catalog #75002)
  • The process of PS translocation occurs prior to the loss of membrane integrity
  • Therefore, as cells progress through apoptosis and towards necrosis, the cell membrane is compromised and consequently, viability dyes pass into the cell
  • Thus, cells undergoing early apoptosis stain positive for Annexin V and negative for viability dyes, while apoptotic death or necrosis is characterized by positive staining for both Annexin V and the viability dye

Specifications

Quantity 25 Tests
For Use With (Application) Flow Cytometry
Conjugate APC (Allophycocyanin)
Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.