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AL 8697, MedChemExpress

Product Code. 16476937
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5 mg
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Product Code. 16476937 Supplier Medchem Express Supplier No. HY108645

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Description

MedChemExpress AL 8697 is a specific and orally active p38α MAPK inhibitor with an IC50 of 6 nM. AL 8697 displays 14-fold greater inhibition of p38α compared to p38β (IC50=82 nM), and 300-fold selectivity for p38α over a panel of 91 kinases. Anti-inflammatory activity.

AL 8697 is a specific and orally active p38α MAPK inhibitor with an IC50 of 6 nM. AL 8697 displays 14-fold greater inhibition of p38α compared to p38β (IC50=82 nM), and 300-fold selectivity for p38α over a panel of 91 kinases. Anti-inflammatory activity.

Specifications

Chemical Name or Material AL 8697
CAS 1057394-06-5
Color White
Purity Grade Notes Research
Molecular Formula C21H21F3N4O
Quantity 5 mg
Solubility Information DMSO : 100 mg/mL (248.50 mM; Need ultrasonic)
SMILES O=C(NC1CC1)C2=CC(F)=C(C)C(C3=C(F)C4=NN=C(C(C)(C)C)N4C=C3F)=C2
Molecular Weight (g/mol) 402.41
Formula Weight 402.41
Percent Purity 99.0%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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