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Eurofins DiscoverX Akt3/PKBγ (S472D) Protein, Active

Product Code. 17340254
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Quantity:
10 μg
250 μg
Unit Size:
10µg
250µg
This item is not returnable. View return policy

Product Code. 17340254

Brand: Eurofins DiscoverX 14502

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This item is not returnable. View return policy

Description

Active, N-terminal His6-tagged, recombinant human Akt3/PKBγ, amino acids 117-end, containing a S472D mutation, for use in Kinase Assays.

AKT (also called protein kinase B) is a serine/threonine protein kinase that has been implicated in mediating a variety of biological responses including inhibiting apoptosis and stimulating cellular growth. Three mammalian isoforms (AKT1, AKT2, and AKT3) of the kinase have been identified.

EMBL AF124141. The recombinant protein contains an amino acid substitution, S472D, with reference toEMBL AF124141. This mutation mimics phosphorylation of S472.

Specifications

Formulation mg/mL of enzyme in 50 mM Tris/HCl, pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol) 43 kDa
Quantity 10 μg
Species Human
Recombinant Recombinant
Protein Tag N-terminal 6His
Expression System Recombinant enzyme expressed in Sf21 insect cells
Protein Form Truncated
Purity or Quality Grade ≥75%
Protein PKB gamma (117-end, S472D), active
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