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Invitrogen™ Adenylate Cyclase 5/6 Polyclonal Antibody
Description
Antibody detects endogenous levels of total ADCY5/6.
Adenylate cyclase 5/6 encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.
Specifications
Specifications
| Antigen | Adenylate Cyclase 5/6 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | ADCY6 |
| Gene Accession No. | O43306, O95622, P84309, Q01341, Q03343, Q04400 |
| Gene Alias | A cyclase V; A cyclase VI; AC5; AC6; ACVI; Adcy5; Adcy6; ADCYB; adenylate cyclase 5; adenylate cyclase 6; adenylate cyclase type 5; Adenylate cyclase type 6; adenylate cyclase type V; Adenylate cyclase type VI; adenylyl cyclase 5; Adenylyl cyclase 6; adenylyl cyclase type V; ATP pyrophosphate-lyase 5; ATP pyrophosphate-lyase 6; AW121902; ca(2+)-inhibitable adenylyl cyclase; FDFM; KIAA0422; LCCS8; mKIAA0422 |
| Gene Symbols | ADCY5, ADCY6 |
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