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Invitrogen™ ACVR2B Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand: Invitrogen™ PA596838

Product Code. 16579671

514.00 € / 100µL

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Description

Immunogen sequence: EGEQDKRLHC YASWRNSSGT IELVKKGCWL DDFNCYDRQE CVATEENPQV YFCCCEGNFC NERFTHLPEA GGPEVTYEPP PTAPTLLTVL AYSLLPIGGL S; Positive Samples: U-87MG, K-562; Cellular Location: Cell membrane, Single-pass type I membrane protein.

ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.

Specifications

Antigen	ACVR2B
Classification	Polyclonal
Conjugate	Unconjugated
Gene	ACVR2B
Gene Alias	activin A receptor type 2B; activin A receptor type IIB; activin A receptor, type IIB; activin receptor IIB; activin receptor type IIB; Activin receptor type-2B; Activine receptor 2b (transmembrane serine kinase); ActRIIB; ACTR-IIB; ActRIIB type II activin receptor B; ACVR2B; HTX4; MGC116908
Host Species	Rabbit
Purification Method	Affinity chromatography
Regulatory Status	RUO
Gene ID (Entrez)	93
Content And Storage	-20°C, Avoid Freeze/Thaw Cycles
Form	Liquid

Applications	ELISA, Western Blot, Immunocytochemistry
Concentration	1.05 mg/mL
Formulation	PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.	Q13705
Gene Symbols	ACVR2B
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ACVR2B (NP_0010972).
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Human
Product Type	Antibody
Isotype	IgG

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Invitrogen™ ACVR2B Polyclonal Antibody

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