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ACE2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16830725 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16830725 20 μL 20µL
16820725 150 μL 150µL
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Product Code. 16830725 Supplier Proteintech Supplier No. 211151AP20UL

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Description

Rabbit Polyclonal Antibody

This antibody is specific to ACE2.

Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.

Specifications

Antigen ACE2
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.43 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ACE2
Gene Accession No. Q5EGZ1, Q8R0I0, Q9BYF1
Gene Alias ACE related carboxypeptidase, ACE2, ACEH, Angiotensin converting enzyme 2, Metalloprotease MPROT15
Gene Symbols ACE2
Host Species Rabbit
Immunogen ACE2 Fusion Protein Ag15455
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 302668, 59272, 70008
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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