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Nigericin sodium salt, 98+%, Thermo Scientific™
A potassium ionophore
Brand: Thermo Scientific Alfa Aesar J61349.MA
146.30 EUR valid until 2026-03-27
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| Quantity | 10mg |
|---|
Description
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
ApplicationsNigericin sodium salt is a polyether ionophore which catalyzes the electroneutral exchange of alkali metal (K+) for H+ (antiport). It disrupts membrane potential and stimulates ATPase activity in mitochondria. It transports monovalent cations across membranes with the following specificity: K+ >Rb+ >Cs+ >>Na. It kills bacteria by facilitating the diffusion of ions across membranes. It is widely used in studies of the consequences of changes in membrane potential in variable systems.
Solubility
Soluble in chloroform, methanol or ethanol
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents, acids, bases and heat.
Specifications
| 28643-80-3 | |
| MFCD00036825 | |
| UN3462 | |
| 14,6541 | |
| Soluble in chloroform, methanol or ethanol | |
| CC1CCC(OC1C(C)C(=O)O)CC2CC(C(C3(O2)C(CC(O3)(C)C4CCC(O4)(C)C5C(CC(O5)C6C(CC(C(O6)(CO)O)C)C)C)C)C)OC | |
| 724.973 | |
| 746.94 | |
| Nigericin sodium salt |
| C40H68O11 | |
| 10mg | |
| 3892398 | |
| nigericin | |
| DANUORFCFTYTSZ-FBMOGUJMSA-N | |
| (2R)-2-[(2R,3S,6R)-6-[[(2S,4R,5R,6R,7R,9R)-2-[(2R,5S)-5-[(3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-7-methoxy-2,4,6-trimethyl-1,10-dioxaspiro[4.5]decan-9-yl]methyl]-3-methyloxan-2- | |
| 123134611 | |
| ≥98% |
Safety and Handling
- Nigericin sodium salt
Signal Word
- Danger
Hazard Category
- Acute toxicity Category 3
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
Hazard Statement
- H301-Toxic if swallowed.
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
Precautionary Statement
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P332+P313-If skin irritation occurs: Get medical advice/attention.
- P337+P313-If eye irritation persists: Get medical advice/attention.
Supplemental information
- MIXTURE LIST-Contain: Nigericin sodium salt
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