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6-Fluoro-2-methylquinoline, 98+%

Product Code. 11430353
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Product Code. 11430353

Brand: Thermo Scientific Alfa Aesar A11469.06

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CAS: 1128-61-6 | C10H8FN | 161.179 g/mol

Metal-free transfer hydrogenation of 6-fluoro-2-methylquinoline by employing several chiral Bronsted acid catalysts was carried out in combination with dihydropyridines as the hydride source in asymmetric metal-free synthesis of fluoroquinolones by organocatalytic hydrogenation. Hydrogenation product of 6-fluoro-2-methylquinoline is the key intermediate of the antibacterial agent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Metal-free transfer hydrogenation of 6-fluoro-2-methylquinoline by employing several chiral Brønsted acid catalysts was carried out in combination with dihydropyridines as the hydride source in asymmetric metal-free synthesis of fluoroquinolones by organocatalytic hydrogenation. Hydrogenation product of 6-fluoro-2-methylquinoline is the key intermediate of the antibacterial agent.

Solubility
Soluble in Chloroform.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1128-61-6
Molecular Formula C10H8FN
Molecular Weight (g/mol) 161.179
MDL Number MFCD00041233
InChI Key GPIARMSVZOEZCV-UHFFFAOYSA-N
Synonym 6-fluoroquinaldine, quinoline, 6-fluoro-2-methyl, 2-methyl-6-fluoroquinoline, 6-fluor-2-methylchinolin, 6-fluoro quinaldine, pubchem7579, acmc-1boyk, maybridge1_000571, 6-fluoro-2-methyl-quinoline, 6-fluoro-2-methyl quinoline
PubChem CID 70784
IUPAC Name 6-fluoro-2-methylquinoline
SMILES CC1=NC2=C(C=C1)C=C(C=C2)F

Specifications

Melting Point 52°C to 56°C
Quantity 5 g
Beilstein 1281677
Solubility Information Soluble in Chloroform.
Formula Weight 161.18
Percent Purity ≥98%
Chemical Name or Material 6-Fluoro-2-methylquinoline

RUO – Research Use Only

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