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5-chloro-2'-deoxyuridine, MP Biomedicals™

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Quantity:
1 g
Unit Size:
1g
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Product Code. 11431912

Brand: MP Biomedicals 0210547891

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Description

Readily incorporated, following phosphorylation, into newly synthesized DNA in place of thymidine. MP Biomedicals’ 5-chloro-2'-deoxyuridine (CldU) can be used as labeling substrate, thymidine analog, or to identify sites of DNA replication. Visible absorb

  • Used as a thymidine analog to study the miscoding potential of hypochlorous acid damage to DNA and DNA precursors
  • When used with antibody based immunofluorescent imaging, may be used in protocols to identify sites of DNA replication
  • May be used as a labeling substrate in conjunction with other halogenated uridine labeling substrates, such as bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU)
TRUSTED_SUSTAINABILITY

Specifications

CAS 50-90-8
Melting Point 166°C to 176°C
Molecular Formula C9H11ClN2O5
Quantity 1 g
Synonym 5-chloro-2'-deoxyuridine
Solubility Information Soluble in 1M NH4OH (20mg/1ml, colorless solution).
InChI Key NJCXGFKPQSFZIB-XVMARJQXSA-N
SMILES C1C(C(OC1N2C=C(C(=O)NC2=O)Cl)CO)O
IUPAC Name 5-chloro-1-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Molecular Weight (g/mol) 262.646
PubChem CID 13831089
Formula Weight 262.6
Physical Form Powder
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Safety and Handling

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Product Identifier
  • 5-Chloro-2'-deoxyuridine
 Signal Word
  • Warning
 Hazard Category
  • Acute toxicity Category 4
  • Carcinogenicity Category 2
 Hazard Statement
  • H302-Harmful if swallowed.
  • H312-Harmful in contact with skin.
  • H332-Harmful if inhaled.
  • H351-Suspected of causing cancer.
 Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
  • P321-Specific treatment (see on this label).
  • P405-Store locked up.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : 5-Chloro-2'-deoxyuridine
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