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Tocris Bioscience™ 3-Mercaptopicolinic acid hydrochloride

Product Code. 18717786
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50 mg
Unit Size:
50mg
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18717786 50 mg 50mg
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Product Code. 18717786 Supplier Tocris Bioscience™ Supplier No. 7577/50

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Description

Phospoenolpyruvate carboxykinase (PEPCK) inhibitor; inhibits gluconeogenesis

3-Mercaptopicolinic acid hydrochloride is a phospoenolpyruvate carboxykinase (PEPCK) inhibitor (IC50 = 7.5 μM at hPEPCK). Inhibits glucose synthesis. In vitro, 3-Mercaptopicolinic acid reduces proliferation of Treg cells, induces myogenic differentiation of C2C12 cells, and reduces colony growth formation of MCF7 cells. Also sensitizes melanoma cells to Vemurafenib (Cat. No. 7309) via inhibition of cytoplasmic PEPCK.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 3-Mercapto-2-pyridinecarboxylic acid hydrochloride
CAS 320386-54-7
Quantity 50 mg
Target PCK1
Molecular Formula C6H5NO2S.HCl
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