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Thermo Scientific™ 2'-OMe-Ac-C Phosphoramidite, standard grade, 20-400 finish bottle

Product Code. 17964242 Shop All Thermo Scientific Products
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Product Code. 17964242 Supplier Thermo Scientific™ Supplier No. 27182310

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2'-OMe-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-O-methyl protection, for use in oligonucleotide synthesis.

2'-OMe-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

Features:
• HPLC purity—≥98.0%; Sum of PIII impurities (140-152ppm) ≤0.5%

TRUSTED_SUSTAINABILITY

Specifications

31P NMR Purity ≥98.0%
Format Amber bottle (20-400 finish neck style)
For Use With (Equipment) Expedite Synthesizers
Description Base: C
Base Protection: Ac
Molecular Weight (g/mol) 801.86 g/mol
Product Type 2in-OMe-Ac-C CEP
Content And Storage Store in freezer (at or below -20°C).
Nucleoside Type Cytidine (C)
Reagent Features 2in-OMe modified, Fast deprotection
Shipping Condition Room Temperature
Purity ≥98% (HPLC)
Quantity 1 g
Reagent Type Phosphoramidite
Grade Standard
Nucleic Acid Type RNA
For Use With (Application) Oligonucleotide synthesis
Form Powder
Chemical Name or Material 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-O-methyl-cytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Molecular Formula C42H52N5O9P
CAS 199593-09-4
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For Research Use Only. Not for use in diagnostic procedures.

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