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1-Trimethylsilylmethanol, 95%

Product Code. 11396856
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Product Code. 11396856 Supplier Thermo Scientific Alfa Aesar Supplier No. L04251.03
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CAS: 3219-63-4 | C4H12OSi | 104.224 g/mol

1-Trimethylsilylmethanol is used as nucleophile to resolve the racemate obtained from enantioselective esterification of naproxen (2-(6-methoxy-2-naphthyl) propionic acid) by lipases. It was also used as a nucleophilic hydroxymethylation agent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Trimethylsilylmethanol is used as nucleophile to resolve the racemate obtained from enantioselective esterification of naproxen (2-(6-methoxy-2-naphthyl) propionic acid) by lipases. It was also used as a nucleophilic hydroxymethylation agent.

Solubility
Fully miscible in water.

Notes
Store at 4°C. Incompatible with oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 3219-63-4
Molecular Formula C4H12OSi
Molecular Weight (g/mol) 104.224
MDL Number MFCD00004596
InChI Key ZQKNBDOVPOZPLY-UHFFFAOYSA-N
Synonym trimethylsilyl methanol, 1-trimethylsilylmethanol, hydroxymethyltrimethylsilane, methanol, trimethylsilyl, silane, hydroxymethyl trimethyl, hydroxymethyl trimethylsilane, trimethylhydroxymethylsilane, methanol, 1-trimethylsilyl, trimethylsilyl-methanol, acmc-209hrr
PubChem CID 76692
IUPAC Name trimethylsilylmethanol
SMILES C[Si](C)(C)CO

Spezifikation

Boiling Point 121°C to 122°C
Quantity 1 g
UN Number UN1993
Beilstein 1731486
Flash Point 31°C (87°F)
Solubility Information Fully miscible in water.
Formula Weight 104.23
Percent Purity ≥98%
Refractive Index 1.419
Density 0.827
Chemical Name or Material 1-Trimethylsilylmethanol
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