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  7. 1-Boc-piperazine, 99%

1-Boc-piperazine, 99%

Product Code. 11378076
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Product Code. 11378076 Supplier Thermo Scientific Alfa Aesar Supplier No. L13363.03
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Description

CAS: 57260-71-6 | C9H19N2O2 | 187.26 g/mol

1-Boc-piperazine is useful for the preparation of (m-phenoxy)phenyl substituted piperazine derivatives. It is also used in the synthesis of indazole DNA gyrase inhibitors. Further, it plays an important role in the preparation of alfa,beta-poly(2-oxazoline) lipopolymers through living cationic ring opening polymerization. It is also in involved in Buchwald-Hartwig coupling reactions with aryl halides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Boc-piperazine is useful for the preparation of (m-phenoxy)phenyl substituted piperazine derivatives. It is also used in the synthesis of indazole DNA gyrase inhibitors. Further, it plays an important role in the preparation of alfa,beta-poly(2-oxazoline) lipopolymers through living cationic ring opening polymerization. It is also in involved in Buchwald-Hartwig coupling reactions with aryl halides.

Solubility
Soluble in ethyl acetate, methanol and water.

Notes
Hygroscopic. Store in a cool place. Moisture sensitive. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 57260-71-6
Molecular Formula C9H19N2O2
Molecular Weight (g/mol) 187.26
MDL Number MFCD00075265
InChI Key CWXPZXBSDSIRCS-UHFFFAOYSA-O
Synonym 1-boc-piperazine, n-boc-piperazine, 1-n-boc-piperazine, tert-butyl 1-piperazinecarboxylate, 1-tert-butoxycarbonyl piperazine, n-t-butoxycarbonylpiperazine, boc-piperazine, n-tert-butoxycarbonylpiperazine, piperazine-1-carboxylic acid tert-butyl ester, 1-piperazinecarboxylic acid, 1,1-dimethylethyl ester
PubChem CID 143452
IUPAC Name tert-butyl piperazine-1-carboxylate
SMILES CC(C)(C)OC(=O)N1CC[NH2+]CC1

Specifications

Melting Point 44°C to 48°C
Quantity 1 g
Beilstein 879985
Sensitivity Air Sensitive
Solubility Information Soluble in ethyl acetate,methanol and water.
Formula Weight 186.26
Percent Purity 99%
Chemical Name or Material 1-Boc-piperazine

RUO – Research Use Only

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