CAS RN 2098836-54-3

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Functionalized VHL ligand for PROTAC™; development

MedChemExpress VH032 thiol (VHL ligand 6) is a VHL ligand, which binds to pan-BET inhibitor JQ1 via a linker to form PROTAC.

Molecular Weight (g/mol)	490.64
Color	Off-White
Physical Form	Solid
Chemical Name or Material	VH032 thiol
Grade	Research
SMILES	CC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@H](C(C)(C)S)NC(C)=O)=O)=O)C=C2
For Use With (Application)	Neuroscience-Neuromodulation
Percent Purity	95.02%
CAS	2098836-54-3
Solubility Information	DMSO : 50 mg/mL (101.91 mM; Need ultrasonic)
Synonym	VHL ligand 6
Purity Grade Notes	Research
Recommended Storage	4°C, stored under argon∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under argon)
Shelf Life	4°C, stored under argon∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under argon)
Molecular Formula	C₂₃H₃₀N₄O₄S₂
Formula Weight	490.64