CAS RN 2097132-94-8

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Pralsetinib, MedChemExpress

MedChemExpress Pralsetinib (BLU-667) is a highly potent, selective RET inhibitor. Pralsetinib (BLU-667) inhibits WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion with IC50s of 0.4, 0.3, 0.4, 0.4, and 0.4 nM, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	533.6
Color	White
Physical Form	Solid
Chemical Name or Material	Pralsetinib
Grade	Research
SMILES	O=C([C@@]1(OC)CC[C@H](C2=NC(NC3=NNC(C)=C3)=CC(C)=N2)CC1)N[C@H](C4=CC=C(N5N=CC(F)=C5)N=C4)C
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.39%
CAS	2097132-94-8
Solubility Information	DMSO : ≥ 100 mg/mL (187.41 mM)
Synonym	BLU-667
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₇H₃₂FN₉O₂
Formula Weight	533.6

CAS RN 2097132-94-8

CAS RN 2097132-94-8

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