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Filtered Search Results
Cercosporamide, MedChemExpress
MedChemExpress Cercosporamide is a highly potent, ATP-competitive Pkc1 kinase inhibitor, with an IC50 of Ki of Mnk inhibitor.
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Troglitazone, MedChemExpress
MedChemExpress Troglitazone is a PPARγ agonist, with EC50s of 550 nM and 780 nM for human and murine PPARγ receptor, respectively.
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| Molecular Weight (g/mol) | 441.54 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Troglitazone |
| Grade | Research |
| SMILES | O=C(SC1CC(C=C2)=CC=C2OCC3(C)OC(C(CC3)=C4C)=C(C)C(C)=C4O)NC1=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 96.46% |
| CAS | 97322-87-7 |
| Solubility Information | DMSO : 160 mg/mL (362.37 mM; Need ultrasonic) |
| Synonym | CS-045 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C24H27NO5S |
| Formula Weight | 441.54 |
Acetosyringone, MedChemExpress
MedChemExpress Acetosyringone is a phenolic compound from wounded plant cells, enables virA gene which encodes a membrane-bound kinase to phosphorylate itself and activate the virG gene product, which stimulates the transcription of other vir genes and itself. Acetosyringone enhances efficient Dunaliella transformation of Agrobacterium strains.
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3-Hydroxymandelic Acid, MedChemExpress
MedChemExpress 3-Hydroxymandelic Acid, a metabolite of Phenylephrine, Phenylephrine is a α-receptor agonist.
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Branaplam, MedChemExpress
MedChemExpress Branaplam (LMI070; NVS-SM1) is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. Branaplam elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model.
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| Molecular Weight (g/mol) | 393.48 |
|---|---|
| Color | Yellow |
| Physical Form | Powder |
| Chemical Name or Material | Branaplam |
| Grade | Research |
| SMILES | OC1=CC(C2=CNN=C2)=CC=C1C3=CC=C(OC4CC(C)(C)NC(C)(C)C4)N=N3 |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 95.62% |
| CAS | 1562338-42-4 |
| Solubility Information | DMSO : 5 mg/mL (12.71 mM; ultrasonic and warming and heat to 80°C) |
| Synonym | LMI070 NVS-SM1 |
| Purity Grade Notes | Research |
| Recommended Storage | 4°C, sealed storage, away from moisture and light∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture and light) |
| Shelf Life | 4°C, sealed storage, away from moisture and light∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture and light) |
| Molecular Formula | C22H27N5O2 |
| Formula Weight | 393.48 |
p-Synephrine, MedChemExpress
MedChemExpress p-Synephrine is an organic compound, found in multiple biofluids, such as urine and blood.
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Kuwanon A, MedChemExpress
MedChemExpress Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.); inhibits nitric oxide production with an IC50 of 10.5 μM.
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| Molecular Weight (g/mol) | 420.45 |
|---|---|
| Color | Light Yellow |
| Physical Form | Solid |
| Chemical Name or Material | Kuwanon A |
| Grade | Research |
| SMILES | O=C1C(C/C=C(C)\C)=C(C2=C3C(C=CC(C)(C)O3)=C(O)C=C2)OC4=CC(O)=CC(O)=C14 |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 96.3% |
| CAS | 62949-77-3 |
| Purity Grade Notes | Research |
| Recommended Storage | 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light) |
| Shelf Life | 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light) |
| Molecular Formula | C25H24O6 |
| Formula Weight | 420.45 |
Tilfrinib, MedChemExpress
MedChemExpress Tilfrinib (compound 4f) is a potent and selective inhibitor of breast tumor kinase (Brk) with an IC50 of 3.15 nM, which displays anti-proliferative activity and acts as a promising antitumor agent.
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Toxicarol isoflavone, MedChemExpress
MedChemExpress Toxicarol isoflavone is an isoflavone extracted from Millettia brandisiana.
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SMER18, MedChemExpress
MedChemExpress SMER18 is a small molecule enhancer of rapamycin which act as a mTOR-independent autophagy inducer.
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| Molecular Weight (g/mol) | 287.74 |
|---|---|
| Color | Yellow |
| Physical Form | Solid |
| Chemical Name or Material | SMER18 |
| Grade | Research |
| SMILES | C/C(NC1=CC=CC(O)=C1)=C/C(C2=CC=C(Cl)C=C2)=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.6% |
| CAS | 944153-47-3 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C16H14ClNO2 |
| Formula Weight | 287.74 |
Tipelukast, MedChemExpress
MedChemExpress Tipelukast (KCA 757) is a sulfidopeptide leukotriene receptor antagonist, an orally bioavailable anti-inflammatory agent and used for the treatment of asthma.
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Didox, MedChemExpress
MedChemExpress Didox (NSC-324360) is a synthetic ribonucleotide reductase (RR) inhibitor.
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| Molecular Weight (g/mol) | 169.13 |
|---|---|
| Color | Earth Yellow |
| Physical Form | Solid |
| Chemical Name or Material | Didox |
| Grade | Research |
| SMILES | O=C(NO)C1=CC=C(O)C(O)=C1 |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.0% |
| CAS | 69839-83-4 |
| Solubility Information | DMSO : 100 mg/mL (591.26 mM; Need ultrasonic) |
| Synonym | NSC-324360 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C7H7NO4 |
| Formula Weight | 169.13 |
AGI-24512, MedChemExpress
MedChemExpress AGI-24512 is a potent methionine adenosyltransferase 2α (MAT2A) inhibitor, with an IC50 of 8 nM. AGI-24512 triggers DNA damage response. AGI-24512 can block proliferation of MTAP-deleted cancer cells in vitro. AGI-24512 can be used for researching anticancer.
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| Molecular Weight (g/mol) | 400.47 |
|---|---|
| Color | Gray |
| Physical Form | Solid |
| Chemical Name or Material | AGI-24512 |
| Grade | Research |
| SMILES | O=C1C(C2=CC=C(O)C=C2)=C(C)NC3=C(N4CCCCC4)C(C5=CC=CC=C5)=NN13 |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 99.48% |
| CAS | 2201066-53-5 |
| Solubility Information | DMSO : 125 mg/mL (312.13 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C24H24N4O2 |
| Formula Weight | 400.47 |
FX-11, MedChemExpress
MedChemExpress FX-11 is a potent, selective, reversible and competitive lactate dehydrogenase A (LDHA) specific inhibitor, with a Ki of 8 μM. FX-11 can effectively activate PKM2 (pyruvate kinase M2). FX-11 reduces ATP levels and induces oxidative stress, ROS production and cell death. FX-11 shows antitumor activity in lymphoma and pancreatic cancer xenografts.
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| Molecular Weight (g/mol) | 350.41 |
|---|---|
| Color | Off-White |
| Physical Form | Solid |
| Chemical Name or Material | FX-11 |
| Grade | Research |
| SMILES | O=C(C1=C2C=C(CC3=CC=CC=C3)C(C)=CC2=C(CCC)C(O)=C1O)O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.44% |
| CAS | 213971-34-7 |
| Solubility Information | DMSO : 250 mg/mL (713.45 mM; Need ultrasonic) |
| Synonym | LDHA Inhibitor FX11 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C22H22O4 |
| Formula Weight | 350.41 |
Dimethyl 4-hydroxyisophthalate, MedChemExpress
MedChemExpress Dimethyl 4-hydroxyisophthalate is a methyl salicylate analogue.
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