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Thermo Scientific SurePac Bio SEC MDi Columns

Bio-inert, uncompromized consistency for size exclusion AAV analysis.

Optimize Aggregate Analysis of AAV-Based Gene Therapies With Thermo Scientific™ SurePac™ Bio SEC MDi™ Columns

Efficient

Baseline resolution of AAV monomers and aggregates in less than four minutes.

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Adaptable

Preserved resolution even for injection of large volumes.

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Reproducible

Consistent separation of AAVs across column lots.

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Applicable Solutions

EVOS S1000 Spatial Imaging System

Extensive Applications - Get The Storage Flexibility You Need

In the field of adeno-associated virus (AAV) analysis, understanding the critical attribute of aggregation is of utmost importance for therapeutic safety and efficacy. View our application note on size-exclusion chromatography of adeno-associated viruses with the SurePac™.

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EVOS S1000 Spatial Imaging System

Choosing the Right Sample Vial for Analysis of AAVs to Prevent Sample Loss

Analysis of viral capsids remains very challenging for numerous reasons. In particular, limited sample availability makes it difficult to maintain high sensitivity and repeatability. In this regard, using the correct sample vials for capsid analysis via liquid chromatography can constitute an important step in allowing for highly reproducible results.

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Related Resources

Liquid Handling Solutions

Understand why the critical attribute of aggregation is important for therapeutic safety and efficacy.

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Related Documentation

Adeno-Associated Viruses (AAVs): Complete Workflow Solutions

Explore different solutions for AAV analysis, depending on your needs.

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Sustain™ Series Low DNA Binding Snap Cap Microcentrifuge Tubes

Chromatography columns and consumables for key biopharma workflows.

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ProPac 3R IEX Columns

Robust. Reproducible. High resolution. Every time.

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Choosing the Right Sample Vial for Analysis of AAV to Prevent Sample Loss

Analysis of viral capsids remains very challenging for numerous reasons.

Download
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Size-Exclusion Chromatography of Adeno-Associated Viruses with the SurePac™ Bio 550 SEC MDi Column

In AAV production, separating the monomeric form from aggregates is critical for optimal gene therapy outcomes.

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Resin Selection Tool

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Looking for other BioLC options, view our large molecule application selector.

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