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  6. N-tert.-Butyl-alpha-Phenylnitron, 98 %, Thermo Scientific Chemicals

N-tert.-Butyl-alpha-Phenylnitron, 98 %, Thermo Scientific Chemicals

Catalog No. 11488027
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Código de producto. 11488027 Proveedor Thermo Scientific Alfa Aesar N.º de proveedor A17442.03
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Descripción

CAS: 3376-24-7 | C11H15NO | 177.247 g/mol

N-tert-Butyl-a-phenylnitrone is a commonly-used free radical trap. It contains radical scavenging activity and an ability to inhibit Cox-2 (cyclooxygenase-2). N-tert-Butyl-a-phenylnitrone is an antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. N-tert-Butyl-a-phenylnitrone inhibits lipid peroxidation in rat liver microsomes. It also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Anwendungen
N-tert-Butyl-a-Phenylnitron ist eine häufig verwendete Freiradikalfalle. Enthält radikale Neutralisierungsaktivität und die Fähigkeit, Cox-2 (Cyclooxygenase-2) zu hemmen. N-tert-Butyl-a-Phenylnitron ist ein Antioxidans, das nachweislich als Schutzmittel in mehreren experimentellen Modellen neurodegenerativer Erkrankungen wirkt. N-tert-Butyl-a-Phenylnitron hemmt die Lipidperoxidation in Mikrosomen der Rattenleber. Verhindert auch die Induktion von induzierbarer Stickoxid-Synthase (iNOS) durch reaktive Sauerstoffspezies.

Löslichkeit
Löslich in DMSO (10 mg/ml), Chloroform (50 mg/ml) und Wasser (20 mg/ml).

Hinweise
Kühl lagern. Reaktiv mit Oxidationsmitteln.
TRUSTED_SUSTAINABILITY

Identificadores de productos químicos

CAS 3376-24-7
Summenformel C11H15NO
Molekulargewicht (g/mol) 177.247
MDL-Nummer MFCD00008799
InChI-Schlüssel IYSYLWYGCWTJSG-FMIVXFBMSA-N
Synonym e-n-benzylidene-2-methylpropan-2-amine oxide
PubChem CID 10313352
IUPAC-Name N-Tert-butyl-1-phenylmethaniminoxid
SMILES CC(C)(C)[N+](=CC1=CC=CC=C1)[O-]

Especificaciones

Chemischer Name oder Material N-tert-Butyl-alpha-phenylnitrone
Schmelzpunkt 71°C to 75°C
Menge 1 g
Beilstein 2044028
Merck Index 14,7056
Löslichkeitsinformationen Soluble in DMSO (10mg/ml),chloroform (50mg/ml),and water (20mg/ml).
Formelmasse 177.25
Reinheit (%) 98%

RUO – Research Use Only

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