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Hydroxyharnstoff, 98 %, Thermo Scientific Chemicals

Catalog No. 11479782
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Product Code. 11479782 Supplier Thermo Scientific Alfa Aesar Supplier No. A10831.06
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CAS: 127-07-1 | CH4N2O2 | 76.055 g/mol

Hydroxyurea is used as an inhibitor of DNA synthesis and an anti-cancer drug. It is used as a precursor to prepare 1-hydroxy-5,6-dimethyl-1H-pyrimidine-2,4-dione via reaction with 2-methyl-3-oxo-butyric acid ethyl ester. It is used in the treatment of melanoma, resistant chronic myelocytic leukemia and recurrent metastatic or inoperable ovarian. It is also involved in reducing the rate of painful attacks in sickle-cell disease and has anti-retroviral properties in diseases such as AIDS.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Löslichkeit
Löslich in Wasser, heißem Alkohol und Dimethylsulfoxid. Unlöslich in Ethanol und Benzol.

Hinweise
Feuchtigkeitsempfindlich. Kühl lagern. Behälter an einem trockenen und gut belüfteten Ort dicht verschlossen halten. Nicht kompatibel mit starken Oxidationsmitteln.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 127-07-1
Summenformel CH4N2O2
Molekulargewicht (g/mol) 76.055
MDL-Nummer MFCD00007943
InChI-Schlüssel VSNHCAURESNICA-UHFFFAOYSA-N
Synonym hydroxycarbamide, n-hydroxyurea, hydrea, 1-hydroxyurea, oxyurea, carbamoyl oxime, biosupressin, hydroxycarbamine, onco-carbide, carbamohydroxamic acid
PubChem CID 3657
ChEBI CHEBI:44423
IUPAC-Name Hydroxyharnstoff
SMILES C(=O)(N)NO

Specifications

Chemischer Name oder Material Hydroxyurea
Schmelzpunkt ∽140°C (decomposition)
Prozentgehaltsbereich 98%
Menge 5 g
Beilstein 1741548
Löslichkeitsinformationen Soluble in water,hot alcohol and dimethyl sulfoxide. Insoluble in ethanol and benzene.
Formelmasse 76.06
compliance-icons
Product Identifier
  • Hydroxyurea
Signal Word
  • Gefahr
Hazard Category
  • Keimzellmutagenität Kategorie 1B
  • Reproduktionstoxizität Kategorie 1A
Hazard Statement
  • H340-Kann genetische Defekte verursachen.
  • H360D-Kann das Kind im Mutterleib schädigen.
Precautionary Statement
  • P201-Vor Gebrauch besondere Anweisungen einholen.
  • P308+P313-BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
Supplemental information
  • MIXTURE LIST-Contain: Hydroxyurea

RUO – Research Use Only

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