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  6. Thermo Scientific™ CaptureSelect™ Biotin Anti-IgG-CH1 Conjugate

Thermo Scientific™ CaptureSelect™ Biotin Anti-IgG-CH1 Conjugate

Catalog No. 18446708 Alle ansehen Thermo Scientific Produkte
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Menge:
100 μg
500 μg
Tamaño de la unidad:
100 Mikrogramm
500 Mikrogramm
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18446708 100 μg 100 Mikrogramm
18406548 500 μg 500 Mikrogramm
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Código de producto. 18446708 Proveedor Thermo Scientific™ N.º de proveedor 7103202100
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Descripción

Thermo Scientific™ CaptureSelect™ Biotin Anti-IgG-CH1 Conjugate consists of a 14 kDa recombinant single domain antibody fragment (VHH affinity ligand) that specifically binds to the CH1 domain of all four human IgG subclasses.

CaptureSelect Biotin Anti-IgG-CH1 Conjugate consists of a 14 kDa recombinant single domain antibody fragment (VHH affinity ligand) that specifically binds to the CH1 domain of all four human IgG subclasses. The affinity ligand is chemically conjugated to biotin via an appropriate spacer that retains the binding reactivity of the ligand when used in combination with streptavidin-based conjugates or streptavidin pre-coated surfaces.

The CaptureSelect Biotin Anti-IgG-CH1 Conjugate allows you to

  • Detect, quantitate, and characterize all human IgG antibodies (subclasses 1 to 4) and Fab fragments thereof, independent of light chain type, and total IgG in human plasma and/or serum samples
  • Avoid cross-binding with other isotypes, such as IgA, IgM, IgD, and IgE, free light chains, or IgG from mouse sources or bovine sources such as FCS
  • Screen antibody-antigen interactions—biotin anti-IgG-CH1 forms a stable [low k(diss)] complex with human IgG antibodies through bivalent binding

Applications for CaptureSelect Biotin Anti-IgG-CH1 Conjugate include ELISA, Western blot, Gyrolab™-based immunoassays, and label-free detection platforms such as those based on surface plasmon resonance (Biacore™ and IBIS-MX96 systems) and bio-layer interferometry (ForteBio™ Octet™ systems).

Animal origin statement

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12–15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

TRUSTED_SUSTAINABILITY

Especificaciones

Inhalt und Lagerung Store at -5°C to -30°C.
Form Flüssig
Produktlinie CaptureSelect
Menge 100 μg
Ziel IgG-CH1
Typ Conjugate
Marker oder Farbstoff Biotin & Other Haptens
Ligandentyp Antikörper
Título del producto
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