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Vimentin Mouse anti-Canine, Chicken, Human, Rat, FITC, Clone: V9, eBioscience™

Mouse Monoclonal Antibody

Marke:  Affymetrix eBioscience 11-9897-82

Weitere Details : Gewicht : 0.25000kg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 15228389

  • 363.00 € / 100 Mikrogramm


Verfügbar ab
14-12-2020
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development. During the development process, vimentin is exchanged for new, tissue-specific IFPs. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.
Spezifikation

Spezifikation

Vimentin
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P31000, P08670, P09654
VIM, FLJ36605
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Canine, Chicken, Human, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
V9
FITC
VIM
Liquid
VIM
IgG1, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
420519, 477991, 7431, 81818
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.