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Tocris Bioscience™ MS 275
GREENER_CHOICE

HDAC (Class I) inhibitor

Brand:  Tocris Bioscience™ 6208/50

Encompass

Product Code. 15766379

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Description

Description

MS 275 is a class I HDAC inhibitor (IC50 values are 0.18, 0.74, 44.9 and >100 μM for HDAC1, 3, 8 and 6, respectively). Exhibits antiproliferative effects and induces apoptosis in a range of tumor cell lines in vitro and in vivo. Increases estrogen receptor α- and aromatase expression in breast cancer cells. Inhibits PCB-induced neuronal cell death by preventing HDAC3 binding and histone deacetylation within the synapsin-1 promoter.
Specifications

Specifications

(Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate
209783-80-2
>99%
50 mg
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