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Ki-67 Mouse anti-Canine, Human, PE, Clone: 20Raj1, eBioscience™

Mouse Monoclonal Antibody

Marke:  Affymetrix eBioscience 12-5699-42

Weitere Details : Gewicht : 0.23750kg

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Artikelnummer. 15527016

  • 302.00 € / 100 Tests


Auf Lager: 3
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Beschreibung

Beschreibung

A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered. Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.
Spezifikation

Spezifikation

Ki-67
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P46013
antigen identified by monoclonal antibody Ki-67; antigen KI-67; KIA; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Canine, Human
Flow Cytometry
20Raj1
PE
MKI67
Liquid
MKI67
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
100686578, 4288
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