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Thermo Scientific Chemicals Indomethacin

Catalog Number p-7077709
22.46 EUR valid until 2024-03-29
Use promo code "21615" to get your promotional price.


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Quantity:
5 g
25 g
100 g
This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
53-86-1
C19H16ClNO4
357.79
CGIGDMFJXJATDK-UHFFFAOYSA-N
indomethacin, indometacin, indocin, indometacine, indomethacine, indocid, metindol, amuno, indomethazine, imbrilon
3715
CHEBI:49662
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O
This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
53-86-1
C19H16ClNO4
357.79
CGIGDMFJXJATDK-UHFFFAOYSA-N
indomethacin, indometacin, indocin, indometacine, indomethacine, indocid, metindol, amuno, indomethazine, imbrilon
3715
CHEBI:49662
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O

Indomethacin, CAS # 53-86-1, is an indole-based nonsteroidal anti-inflammatory (NSAID).

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Indomethacin is a synthetic NSAID of the indole family that inhibits cyclooxygenase and reduces prostaglandin and pyrogen release

• Indomethacin may suppress the multi-drug resistant transporter and thereby increase the efficacy of antineoplastics

• Indomethacin activates phosphatases that inhibit signaling pathways associated with cancer cell migration and proliferation

Applications

• Indomethacin may be used for the laboratory study of cancer cell proliferation, tumorigenesis and drug interactions

• Indomethacin may be used for laboratory study of the effect of inhibiting the multi-drug resistance transporter, or for downregulation of survival signaling in cells via survivin

TRUSTED_SUSTAINABILITY
Melting Point 155.0°C
Loss on Drying 0.5% max. (100°C, 2 h, 5 mm Hg)
Infrared Spectrum Authentic
Quantity 5 g
Formula Weight 357.79
Percent Purity ≥97.5% (HPLC)
Chemical Name or Material Indomethacin
compliance-icons compliance-icons
Product Identifier
  • Indomethacin
Signal Word
  • Danger
Hazard Category
  • Acute toxicity Category 1
  • Skin sensitiser Category 1
  • Reproductive toxicity Category 1B
Hazard Statement
  • H300-Fatal if swallowed.
  • H317-May cause an allergic skin reaction.
  • H360FD-May damage fertility. May damage the unborn child.
Precautionary Statement
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P330-Rinse mouth.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P201-Obtain special instructions before use.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.

RUO – Research Use Only

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