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Abnova™ Human PANK2 Partial ORF (NP_705902.2, 437 a.a. - 570 a.a.) Recombinant Protein with GST-tag at N-terminal

Liquid

Brand:  Abnova™ H00080025-Q01.10ug

Additional Details : Weight : 0.02000kg

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Product Code. 16055655

  • 359.00 € / 10µg

Estimated Shipment: 16-11-2022
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Description

Description

This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq]

Sequence: MASRGDSTKVDKLVRDIYGGDYERFGLPGWAVASSFGNMMSKEKREAVSKEDLARATLITITNNIGSIARMCALNENINQVVFVGNFLRINTIAMRLLAYALDYWSKGQLKALFSEHEGYFGAVGALLELLKIP
Specifications

Specifications

NP_705902.2
Liquid
80025
PANK2 (Human) Recombinant Protein (Q01)
10 ug
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
C20orf48/FLJ17232/HARP/HSS/MGC15053/NBIA1/PKAN
PANK2
Yes
wheat germ expression system
Antibody Production, Enzyme-linked Immunoabsorbent Assay, Protein Array, Western Blot (Recombinant protein)
50mM Tris-HCI, 10mM reduced Glutathione, pH=8.0 in the elution buffer.
41.2kDa
12.5% SDS-PAGE Stained with Coomassie Blue
MASRGDSTKVDKLVRDIYGGDYERFGLPGWAVASSFGNMMSKEKREAVSKEDLARATLITITNNIGSIARMCALNENINQVVFVGNFLRINTIAMRLLAYALDYWSKGQLKALFSEHEGYFGAVGALLELLKIP
RUO
PANK2
Wheat Germ (in vitro)
GST
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