missing translation for 'onlineSavingsMsg'
Learn More

HLA-A3 Mouse anti-Human, FITC, Clone: GAP.A3, eBioscience™

Mouse Monoclonal Antibody

Marke:  Affymetrix eBioscience 11-5754-41

Weitere Details : Gewicht : 0.23750kg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 15526566

  • 123.00 € / 25 Tests


Geschätzter Ausliefertermin
von Anbieter 03-04-2020
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described.
Spezifikation

Spezifikation

HLA-A3
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P05534
HLA-A
IgG2a, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
3105
Flow Cytometry
GAP.A3
FITC
HLA-A
Liquid
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Videos
Dokumentation

For Research Use Only.