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GM-CSF Rat anti-Mouse, FITC, Clone: MP1-22E9, eBioscience™

Rat Monoclonal Antibody

Marke:  Affymetrix eBioscience 11-7331-41

Weitere Details : Gewicht : 0.23750kg

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Artikelnummer. 15526606

  • 75.75 € / 25 Tests


Geschätzter Ausliefertermin
von Anbieter 28-02-2020
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Beschreibung

Beschreibung

GM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The active form of the GM-CSF protein is found extracellularly as a homodimer and the GM-CSF gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. The ability of recombit GM-CSF to increase hematopoietic cell recovery has become a focus area in the therapeutic treatment of patients following bone marrow transplantation. Recent studies have investigated GM-CSF in inflammatory and autoimmune diseases such as arthritis, arthritis related interstitial lung disease, nephritis, and psoriasis. In the CNS, GM-CSF depletion or neutralization has been studied in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS).
Spezifikation

Spezifikation

GM-CSF
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P01587
Granulocyte Macrophage Colony Stimulating Factor, Colony-stimulating factor, CSF, Sargramostim, Molgramostin
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
MP1-22E9
FITC
Csf2
Liquid
Csf2
IgG2a, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
12981
Videos
Dokumentation

For Research Use Only.