GILZ Rat anti-Human, Mouse, Clone: CFMKG15, eBioscience™
Rat Monoclonal Antibody
Marke: Affymetrix eBioscience 14-4033-82
Weitere Details : Gewicht : 0.01000kg
BeschreibungThis can be used at less than or equal to 2 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-Kappa-B and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-Kappa-B. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.
|PBS with 0.09% sodium azide; pH 7.2|
|TSC22D3, TSC22 domain family member 3, TSC-22 related protein, delta sleep inducing peptide, DIP, DSIPI, GILZ, TSC-22R, DSIP-immunoreactive leucine zipper protein|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot|
For Research Use Only.