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Invitrogen™ Silencer™ Select Human GPCR siRNA Library V4
For the first time, you can obtain the benefits of Invitrogen™Silencer™ Select siRNAs in a convenient pre-plated, library format. These siRNA collections enable medium and high throughput analysis of phenotypes resulting from inhibition of large sets of targets from specific functional classes.
Brand: Invitrogen™ 4397916
Additional Details : Weight : 0.00450kg
Description
Human GPCR siRNA LibraryG protein-coupled receptors, or GPCRs, are key components of many signal transduction pathways and also represent an important class of druggable genes. The Silencer™ Select Human GPCR siRNA Library V4 targets 379 non-olfactory human GPCRs with three individual Silencer™ Select siRNAs per target supplied in 96-well plates.What are Silencer™ Select siRNAs?Silencer™ Select siRNAs are the next generation Invitrogen™ siRNAs. These siRNAs incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemical modifications to yield siRNAs with unrivalled efficacy, potency, and specificity. In siRNA screening applications, the result is fewer false negatives due to poor silencing and fewer false positives due to off target effects. In other words, with Silencer™ Select siRNAs you get cleaner, more consistent data from your primary screen, so you expend less time and resources to find true, validated targets. The result is fewer failed experiments due to poor silencing, and cleaner, more consistent phenotypic data.- Ready-to-ship collections of Invitrogen™ Silencer™ Select siRNAs to popular human gene classes
- Three individual siRNAs per target provided in a convenient 96-well format
- Designed with an all new algorithm that yields better, more consistent knockdown
- Novel chemical modifications reduce off-target effects by up to 90%
- Up to 100 fold more potent than currently available siRNAs
- Demonstrated improvements in consistency and reliability of phenotypic results
Specifications
Contains 1137 unique siRNAs (0.25 nmol) targeting each of 379 human GPCR genes. Total of (15) 96-well plates: (12) plates with 88 siRNAs each. (3) plates with 28 siRNAs each. See the accompanying CD for annotation information and siRNA details. |
For research use only. Not for use in diagnostic procedures