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CD95 (APO-1/Fas) Mouse anti-Canine, Human, Clone: DX2, eBioscience™

Mouse Monoclonal Antibody

Marke:  Affymetrix eBioscience 14-0959-80

Weitere Details : Gewicht : 0.01000kg

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Artikelnummer. 15237127

  • 79.00 € / 25 Mikrogramm


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von Anbieter 04-07-2019
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Beschreibung

Beschreibung

CD95 (Fas, APO-1), a 46 kDa transmembrane glycoprotein, is a cell death receptor of the TNFR superfamily. Stimulation of CD95 results in aggregation of its intracellular death domains, formation of the death-inducing signaling complex (DISC) and activation of caspases. In type I cells caspase 3 is activated by high amounts of caspase 8 generated at the DISC, in type II cells low concentration of caspase 8 activates pathway leading to the release of cytochrome c from mitochondria and activation of caspase 3 by cytochom c. Besides its roles in induction of apoptosis, Fas also triggers pro-inflammatory cytokine responses.
Spezifikation

Spezifikation

CD95 (APO-1/Fas)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P25445
ALPS1A, APO-1, APT1, Apo-1 Fas, CD95, FAS1, FASTM, TNFRSF6
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Canine, Human
Flow Cytometry, Functional Assay, Immunohistochemistry
DX2
Unconjugated
FAS
Liquid
FAS
IgG1, kappa
25 μg
4° C
Primary
355, 486469
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