CD8a, clone: C8/144B, eBioscience™
Mouse Monoclonal Antibody
Marke: Affymetrix eBioscience 14-0085-80
Weitere Details : Gewicht : 0.01000kg
BeschreibungDescription: The monoclonal antibody C8/144B recognizes the human CD8a molecule, an approximately 32-34kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.Applications Reported: This C8/144B antibody has been reported for use in immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.Applications Tested: This C8/144B antibody has been tested by immunohistochemistry on formalin-fixed paraffin embedded human tonsil tissue using IHC Antigen Retrieval Solution - High pH (cat. 00-4956). This can be used at less than or equal to 5 ug/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.09% sodium azide; pH 7.2|
|CD8, Leu-2, MAL, p32, CD8a|
|IgG1, kappa, kappa|
|Store at 2-8°C.|
For Research Use Only.