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CD71 (Transferrin Receptor) Rat anti-Mouse, Clone: R17217 (RI7 217.1.4), eBioscience™

Rat Monoclonal Antibody

Marke:  Affymetrix eBioscience 14-0711-85

Weitere Details : Gewicht : 0.01000kg

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Artikelnummer. 15237067

  • 225.00 € / 500 Mikrogramm


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von Anbieter 02-07-2019
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Beschreibung

Beschreibung

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregcy, irritable bowel syndrome and in HIV patients.
Spezifikation

Spezifikation

CD71 (Transferrin Receptor)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q62351
CD71, T9, TFR, TFR1, TR, TRFR, p90, transferrin receptor protein 1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry, Functional Assay
R17217 (RI7 217.1.4)
Unconjugated
Tfrc
Liquid
Tfrc
IgG2a, kappa
500 μg
4° C
Primary
22042
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