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CD70, clone: FR70, eBioscience™

Rat Monoclonal Antibody

Marke:  Affymetrix eBioscience 14-0701-81

Weitere Details : Gewicht : 0.01000kg

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Artikelnummer. 15297057

  • 43.67 € / 50 Mikrogramm


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von Anbieter 20-09-2018
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Beschreibung

Beschreibung

Description: The FR70 monoclonal antibody reacts with mouse CD70, a 30-33kDa type II transmembrane glycoprotein. CD70 is a member of the TNF family and is expressed by activated mouse T and B lymphocytes. Interaction of CD70 with CD27, its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.Applications Reported: The FR70 antibody has been reported for use in flow cytometric analysis, and immunoprecipitation. FR70 has also been reported in blocking of CD70 in vitro . (Please use Functional Grade purified FR70, cat. 16-0701, in functional assays.).Applications Tested: The FR70 antibody has been tested by flow cytometric analysis of LPS-stimulated mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Spezifikation

Spezifikation

CD70
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
O55237
CD27LG, Cd27l, Tnfsf7
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow CytometryþFunctional AssayþImmunoprecipitationþNeutralization
FR70
Unconjugated
Cd70
Liquid
Cd70
IgG2b, kappa, kappa
50μg
Store at 2-8°C.
Primary
21948
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