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CD7 Mouse anti-Human, APC, Clone: 4H9, eBioscience™

Mouse Monoclonal Antibody

Marke:  Affymetrix eBioscience 17-0078-41

Weitere Details : Gewicht : 0.23750kg

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Artikelnummer. 15527866

  • 93.50 € / 25 Tests


Geschätzter Ausliefertermin
von Anbieter 30-03-2020
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Beschreibung

Beschreibung

CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily. CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on maligt B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3′-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Expression of CD7 is an important marker used in leukemia diagnostics.
Spezifikation

Spezifikation

CD7
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P09564
GP40, LEU-9, TP41, Tp40
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
4H9
APC
CD7
Liquid
CD7
IgG2a, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
924
Videos
Dokumentation

For Research Use Only.