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CD66c Mouse anti-Human, PE, Clone: KOR-SA3544, eBioscience™

Mouse Monoclonal Antibody

Marke:  Affymetrix eBioscience 12-0667-41

Weitere Details : Gewicht : 0.23750kg

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Artikelnummer. 15526816

  • 102.00 € / 25 Tests


Auf Lager: 3
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Beschreibung

Beschreibung

CEACAM1 (BGP/CD66a) is a transmembrane glycoprotein which belongs to the carcinoembryonic antigen (CEA) gene family. It is expressed on cells of epithelial and myeloid origin and mediates homophilic intercellular interactions that influence cellular growth, immune cell activation, and tissue morphogenesis. CEACAM1 is a putative tumour suppressor based on diminished expression in some aggressive types of cancer cells. The anti-tumour effect may be due to inhibition of tumour angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A (A1, A2) and one B domain. While the N, A1 and B domains can also be found in other CEA-family members, the A2 domain of CEACAM1 differs from those found in other CEACAM.
Spezifikation

Spezifikation

CD66c
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P40199
CD66c, CEAL, NCA, carcinoembryonic antigen-related cell adhesion molecule 6, non-specific crossreacting antigen, normal cross-reacting antigen
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
KOR-SA3544
PE
CEACAM6
Liquid
CEACAM6
IgG1, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
4680
Videos
Dokumentation

For Research Use Only.