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CD41a Rat anti-Mouse, Clone: eBioMWReg30 (MWReg30), eBioscience™

Rat Monoclonal Antibody

Marke:  Affymetrix eBioscience 14-0411-85

Weitere Details : Gewicht : 0.01000kg

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Artikelnummer. 15236947

  • 257.00 € / 500 Mikrogramm


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Beschreibung

Beschreibung

A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.
Spezifikation

Spezifikation

CD41a
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q9QUM0
BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3, GPalpha IIb, integrin alpha-IIb, platelet fibrinogen receptor, alpha subunit, platelet membrane glycoprotein IIb, platelet-specific antigen BAK, ITGA2B
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
ELISA, Flow Cytometry, Functional Assay, Immunoprecipitation
eBioMWReg30 (MWReg30)
Unconjugated
Itga2b
Liquid
Itga2b
IgG1, kappa
500 μg
4° C
Primary
16399
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