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CD278 (ICOS) Monoclonal Antibody (7E.17G9), FITC, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
104.00 € - 213.00 €
Specifications
Antigen | CD278 (ICOS) |
---|---|
Clone | 7E.17G9 |
Concentration | 0.5 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15208399
|
Affymetrix eBioscience
11-9942-80 |
25 μg |
104.00 €
25µg |
Estimated Shipment: 31-05-2024 Log in to see stock. |
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15218399
|
Affymetrix eBioscience
11-9942-82 |
100 μg |
213.00 €
100µg |
In Stock Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Description: The 7E.17G9 monoclonal antibody reacts with mouse ICOS (Inducible COStimulatory molecule), a T cell specific molecule and a third member of the CD28/CTLA-4 family. A homodimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response. ICOS binds to its ligand on activated APC including B cells called B7h/B7RP-1 and is thought to play a protective role in inflammatory autoimmune diseases. ICOS may be involved in the development of Th2 cells. Applications Reported: This 7E.17G9 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 7E.17G9 antibody has been tested by flow cytometric analysis of Con A-stimulated mouse splenocytes. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered.
ICOS (CD278) encodes a protein that is a member of the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and has a crucial role in cell-cell signaling, immune responses, and the regulation of cell proliferation. ICOS has been linked to various disorders, including Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.Specifications
CD278 (ICOS) | |
0.5 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 0.09% sodium azide; pH 7.2 | |
Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115 | |
ICOS | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
ICOS |
7E.17G9 | |
Flow Cytometry | |
FITC | |
Rat | |
Mouse | |
Q9WVS0 | |
54167 | |
IgG2b κ | |
Affinity chromatography | |
Antibody |
For Research Use Only.