CD273 (B7-DC) Mouse anti-Human, APC, Clone: MIH18, eBioscience™
Mouse Monoclonal Antibody
Marke: Affymetrix eBioscience 17-5888-42
Weitere Details : Gewicht : 0.23750kg
BeschreibungCell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is specific to the largest isoform. PDL-2 antibody has no cross-reactivity to PDL-2.
|PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2|
|B7-DC, Btdc, F730015O22Rik, MGC124039, MGC124040, PD-L2|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.