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CD273 (B7-DC) Mouse anti-Human, APC, Clone: MIH18, eBioscience™

Mouse Monoclonal Antibody

Marke:  Affymetrix eBioscience 17-5888-42

Weitere Details : Gewicht : 0.23750kg

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Artikelnummer. 15528156

  • 280.00 € / 100 Tests


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von Anbieter 03-03-2020
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Beschreibung

Beschreibung

Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is specific to the largest isoform. PDL-2 antibody has no cross-reactivity to PDL-2.
Spezifikation

Spezifikation

CD273 (B7-DC)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q9BQ51
B7-DC, Btdc, F730015O22Rik, MGC124039, MGC124040, PD-L2
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
MIH18
APC
PDCD1LG2
Liquid
PDCD1LG2
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
80380
Videos
Dokumentation

For Research Use Only.