CD252 (OX40 Ligand) Rat anti-Mouse, PE, Clone: RM134L, eBioscience™
Rat Monoclonal Antibody
Marke: Affymetrix eBioscience 12-5905-82
Weitere Details : Gewicht : 0.25000kg
BeschreibungThe tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predomitly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
|CD252 (OX40 Ligand)|
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|Ath-1, Ath1, TXGP1, Txgp1l, gp34, TNFSF4, CD252, OX40 Ligand|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.