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CD200 Mouse anti-Human, Clone: OX104, eBioscience™

Mouse Monoclonal Antibody

Marke:  Affymetrix eBioscience 14-9200-80

Weitere Details : Gewicht : 0.01000kg

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Artikelnummer. 15238157

  • 54.00 € / 25 Mikrogramm


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von Anbieter 27-08-2019
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Beschreibung

Beschreibung

Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
Spezifikation

Spezifikation

CD200
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P41217
MOX1
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Immunohistochemistry (Frozen)
OX104
Unconjugated
CD200
Liquid
CD200
IgG1, kappa
25 μg
4° C
Primary
4345
Videos
Dokumentation

For Research Use Only.