CD153 Rat anti-Mouse, Clone: RM153, eBioscience™
Rat Monoclonal Antibody
Marke: Affymetrix eBioscience 14-1531-85
Weitere Details : Gewicht : 0.01000kg
Beschreibung2 μm post-manufacturing filtered. The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin′s disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin′s and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin′s lymphomas (including Burkitt′s lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.
|PBS with 0.09% sodium azide; pH 7.2|
|CD153; CD153 antigen; CD30 antigen ligand; CD30 ligand; CD30-L; CD30L; CD30LG; TNFSF8; tumor necrosis factor (ligand) superfamily member 8; tumor necrosis factor (ligand) superfamily, member 8; tumor necrosis factor ligand 3A; tumor necrosis factor ligand superfamily member 8|
|Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Neutralization|
For Research Use Only.