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BI-671800, MedChemExpress

Product Code. 16485586
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Product Code. 16485586

Brand: Medchem Express HY114141

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Description

MedChemExpress BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has potential for the treatment of poorly controlled asthma.

BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has potential for the treatment of poorly controlled asthma.

Specifications

Chemical Name or Material BI-671800
Physical Form Solid
CAS 1093108-50-9
Color White
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C25H26F3N5O3
For Use With (Application) COVID-19-immunoregulation
Solubility Information DMSO : 135 mg/mL (269.19 mM; Need ultrasonic)
SMILES O=C(O)CC1=C(N(C)C)N=C(CC2=CC=C(NC(C3=CC=C(C(F)(F)F)C=C3)=O)C=C2)N=C1N(C)C
Molecular Weight (g/mol) 501.5
Formula Weight 501.5
Percent Purity 99.23%
Grade Research
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Research purposes only

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